Friday June 24th

Friday June 24th                    
VENUE: Pieterskerk, Kloksteeg 16, Leiden
 08:30 - end Registration Desk Available
Session V: Techniques and models to assess cerebrovascular function
  Chairs: Danica Stanimirovic (University of Ottawa, CAN) &
  Robert Thorne (New York University School of Medicine, USA)
 08:30 - 09:00 Danica Stanimirovic (University of Ottawa, CAN)
  Methods to interrogate blood-brain barrier function:in vitro-in vivo paradigms
 09:00 - 09:20 Eric Shusta (University of Wisconsin-Madison, USA)
  Human blood-brain barrier endothelial cells derived from pluripotent stem cells
 09:20 - 09:40 Robert Thorne (University of Wisconsin-Madison, USA)
  Macromolecule transport in the brain
 09:40 - 10:00 Klaus Petry (INSERM Bordeaux, FR)
  Imaging blood-brain barrier function in neuroinflammation
   
 10:00 - 10:30 Break
 10:30 - 10:45 Hadassah Sade (Roche, DE)
  hCMEC/D3 Brain Endothelial Cells as Model System for Transcytosis
 10:45 - 11:00 Mehmet Fidanboylu (King's College, UK)
  L-Arginine and ADMA transport across the in vivo murine BBB and the implications for Nitric Oxide regulation and production in health and disease
 11:00 - 11:15 Hans Christian Helms (University of Copenhagen, DK)
  Bovine endothelial/rat astrocyte co-cultures cultured in higly buffered media functionally express MDR1 and BCRP
 11:15 - 11:30 Andries van der Meer (University of Twente, NL)
  A microfluidic model of the human blood-brain barrier
 11:30 - 11:45 William Fauquette (IRBA-CRSSA, FR)
  Biological response of in vitro BBB after microbeam radiation therapy exposure
 11:45 - 12:00 Joanna Wisniewska-Kruk (Academic Medical Center Amsterdam, NL)
  Development of a new blood-retina model in vitro
   
 12:00 - 13:30 Lunch and poster viewing
 12:15 - 13:15 Business meeting (Organizing and Scientific Committees)
       Selection of CVB 2013 venue
   
Session VI: Blood-brain barrier alterations in neurological disorders
   [sponsored by MedImmune]
  Chairs: Reina Bendayan (University of Toronto, Canada) &
  Alon Friedman (University of Ber-Sheva, IL)
 13:30 - 14:00 Alon Friedman (University of Ber-Sheva, IL)
  Blood-brain barrier dysfunction, epileptogenesis and neurodegeneration:
  a puzzle of a chicken and eggs?
 14:00 - 14:30
Maurizio Scarpa (University of Padova, IT)
  Approaches to cross the blood-brain barrier in lysosomal storage disorders
 14:30 - 15:00
Reina Bendayan (University of Toronto, CAN)
  Antiretroviral drug transporters and HIV infection of the brain
   
 15:00 - 15:30
Break
 
  15:30 - 15:45 Anne Mahringer (Ruprecht-Karls University Heidelberg, DE)
  Influence of alpha-synuclein on P-glycoprotein at the blood-brain barrier in Parkinson's disease
 15:45 - 16:00 Anika Hartz (University of Minnesota, USA)
  Blood-brain barrier P-glycoprotein: a new target for Alzheimer's disease?
 16:00 - 16:15 Gul Shah (Saint Louis University, USA)
  Diabetes-induced oxidative damage to mouse blood-brain barrier: Possible protection by carbonic anhydrase inhibition
 16:15 - 16:30 Akihiko Urayama (University of Texas Medical School, USA)
  Contribution of circulation amyloid-beta to cerebral pathology of Alzheimer's disease
 16:30 - 16:45 Pietra Candela (Université Lille Nord de France, FR)
  Is LRP1 involved in the clearance fo cerebral Aβ peptides? Use of an in vitro BBB model
 16:45 - 17:00 Jianming Xiang (University of Michigan, USA)
  Protective effects of isothiocyanates on blood-CSF barrier disruption induced by oxidative stress
   
 17:15 - 18:15
Social Event : City tour of Leiden
   
 19:30 - 22:00
Conference Gala Dinner (Pieterskerk, Kloksteeg 16, Leiden)